This compact benchtop analyzer uti- lizes a patented laser absorption technique de- veloped with funding from the Food and Drug Administration. How do I register? This compact analyzer utilizes a patented laser absorption technique developed with funding from the Food and Drug Administration. The FMS-Carbon Dioxide is a non-destructive headspace carbon dioxide analyzer from LIGHTHOUSE, the industry leader in laser-based headspace analysis. Once equilibrated, three random vials from each lot were analyzed using the Lighthouse Instruments Headspace Moisture Analyzer (FMS 1400H, Charlottesville, VA) to confirm both the moisture concentration and uniformity of the prepared standards. 2020 Avon Ct Charlottesville VA 22902. LIGHTHOUSE draws on its years of innovation and expertise to bring you top-of-the-line, robust equipment to keep your products, and by extension patients, healthy and safe. Operators do not require special expertise to run the system meaning the . At LIGHTHOUSE we deliver laser-based headspace analyzer platforms and measurement services addressing a wide range of applications for monitoring sterile pharmaceutical processes and inspecting the quality of finished product. Developed with funding from US-FDA, their products non-destructively monitor headspace oxygen, moisture and pressure levels on parenteral containers. It can be used in nondestructive residual oxygen analysis, container seal integrity test, product . Description: The FMS-1400 Headspace Pressure/Moisture Analyzer is a non-destructive gas analyzer for simultaneously monitoring moisture partial pressure and total headspace pressure in sealed parenteral containers. In order to achieve the best performance when using headspace/GC, careful atten-tion should be used in sample preparation and instrument setup. Compliance with regulations: USP<1207> , EU GMP, CDE Conformance Evaluation, ASTM F2338-09(2013) . The sameA LIGHTHOUSE FMS-760 headspace oxygen analyzer vial was evaluated with a grey butyl and a teflon coat-was used to test the entire batch for the presence of ed stopper. LIGHTHOUSE's FMS-Oxygen Headspace Analyzer measures oxygen concentration in sealed parenteral containers. LIGHTHOUSE continues to innovate the use of rapid, non-destructive headspace gas analysis. LIGHTHOUSE LIGHTHOUSE Instruments is the global provider non-destructive headspace analysis systems that ensure the quality of parenteral products. This compact benchtop instrument utilizes a patented laser absorption technique developed with funding from the Food and Drug Administration. In addition to delivering equipment . Lighthouse-Instruments-Water-Activity-Analyzer-for-headspace-inspection. SKU: H50479IN Category . Rapid, nondestructive, laser-based headspace analysis is suitable for applications specific to the sterile pharmaceutical industry. . Lighthouse FMS-760 Headspace Oxygen Analyzer. Headspace Oxygen Analyzer The FMS-Oxygen Headspace Analyzer is a non-destructive gas analyzer for monitoring headspace oxygen concentration in sealed parenteral containers. . The non-destructive and rapid optical method is perfectly suited to test each container even of large batches. The Lighthouse Instruments FMS-1400 Headspace Pressure Analyzer was designed to monitor headspace oxygen concentration in the headspace of the prefilled syringe for a nondestructive gas analyzer. Vials with greater than be stoppered at 414 torr (550 mbar) of nitrogen. Headspace pressure and oxygen content measurements were made using a Lighthouse non-destructive headspace oxygen analyzer. LIGHTHOUSE The Science of Pharmaceutical Manufacturing Figure 2: Benchtop headspace analyzer Headspace Inspection Systems Diode laser based systems can be configured in a variety of ways to monitor and control processes and / or inspect individual containers for headspace oxygen, moisture or vacuum. Transparent or amber vials, syringes, and cartridges with a minimum headspace volume and . . Process technology. Key issues to address when setting up headspace/GC systems include minimizing . The automated VISTA Headspace Oxygen Inspection Machine enables automated 100% inspection of headspace oxygen levels in sealed parenteral containers. TDLAS-Based Water Vapor Mass Flow Rate Monitor. We introduced laser-based headspace analysis into the pharmaceutical industry in 2000 with the help of funding from the Food and Drug Administration. LIGHTHOUSE is the leading global provider of laser-based, non-destructive headspace inspection systems. The benchtop headspace oxygen analyzer can be used throughout the entire product lifecycle, from development to QC laboratory applications to at-line, in-process control of headspace oxygen levels and production. This headspace gas analyzer utilizes a tunable diode laser absorption spectroscopy technique that employs frequency modulation to enhance measurement sensitivity. Seller's Acceptable Currency: Best offer. LIGHTHOUSE Instruments | 2.465 seguidores no LinkedIn. Contact Us It helps to reliably detect temporary or permanent leaks. Press release - Report Ocean - Headspace Gas Analyzers Market research key players, industry overview, supply chain and analysis to 2021 to 2027 - published on openPR.com It is a useful analytical tool to generate statistical process and product data in all stages of the product life cycle, from Development to Manufacturing and Quality Control. Based on our industrial analyzer platform, this analyzer includes a built-in pump that is easy to use and very portable. The compact benchtop instrument utilizes a patented laser absorption technique developed with funding from the Food and Drug Administration. Rapid Non-destructive Headspace Analyzers. The lyophilized product was specified tooxygen in the vial headspace. The compact benchtop instrument utilizes a patented laser absorption technique developed with funding from the Food and Drug Administration. The compact benchtop instrument utilizes a patented laser absorption technique developed with funding from the Food and Drug Administration. An increase of 1 torr in the headspace carbon dioxide content after completion of the pressure cycling procedure was intended to serve as confirmation of leak detection. LIGHTHOUSE Instruments is the leading provider and manufacturer of headspace analysis platforms and measurement services. LIGHTHOUSE FMS-Oxygen Headspace Analyzer The FMS-Oxygen Headspace Analyzer is a non- destructive gas analyzer for monitoring head- space oxygen concentration in sealed parenteral containers. Therefore, the headspace was purged with . An aliquot of the vapor in the headspace is delivered to a GC system for separation of all of the volatile components. The MarketWatch News Department was not involved in the creation of this content. Lighthouse Instruments provides state-of-the-art, laser-based systems for rapid non-destructive headspace analysis of sterile drug products. From there, the gas is passed to sensors that reside within the analyzer. Website. Lighthouse - FMS-760 Flexible Bag Headspace Analyzer Lighthouse Instruments, LLC, is the leading provider of optical-based, non-destructive headspace inspection systems for product R&D, at-line and in-line applications specific to the pharmaceutical, biotechnology and contract manufacturing industry. The device has a built-in pump that withdraws a gas sample from a packaged food product using a small probe or syringe. The FMS-Oxygen Headspace Analyzer is a non-destructive gas analyzer for monitoring headspace oxygen concentration in sealed parenteral containers. It can also be used to determine the rate of . Email info@lighthouseinstruments.com Phone Number (434) 293-3081 Recent Job Listings Automated package sampling is easy. The benchtop FMS-Pressure/Moisture Headspace Analyzer can be utilized throughout the product lifecycle for development and QC laboratory applications, as well as final inspection of headspace moisture and pressure levels in production and packaging. The supplier, Lighthouse Instruments, is the leader in nondestructive laser-based headspace analysis and its suite of instruments include the Headspace Analyzers (for Oxygen, Carbon Dioxide, and Moisture/Pressure) and Container Closure Integrity Test Vessel, enabling gas ingress (leak) testing and the generation of robust statistical CCI data. Lighthouse Case Studies. LIGHTHOUSE has engineered a variety of rapid, non-destructive headspace analysis platforms. Typical applications include 100% container closure "At Gilead we use Lighthouse's FMS benchtop headspace moisture/pressure analyzer to nondestructively confirm the integrity of developmental and investigatory vials. Lighthouse Product Notes FMS-Carbon Dioxide Headspace Analyzer Datasheet 7/29/2020 The FMS-Carbon Dioxide analyzer measures the headspace carbon dioxide levels of sterile pharmaceutical containers non-destructively, in development, manufacturing and QC. This system can be used for CCI testing of frozen product in storage or transport studies. Specifications: - Electrical Data: 120 v, 60 Hz, 2 AMPS. Headspace analyzers are sometimes called MAP analyzers or food packaging analyzers. Rapid, nondestructive, laser-based headspace analysis is suitable for applications specific to the sterile pharmaceutical . You can register on our website using the exact company name that is on your company's W-9 or corporate return. There is an accepted offer on this item already. The benchtop headspace oxygen analyzer can be used throughout the entire product lifecycle, from development to QC laboratory applications to at-line, in-process control of headspace oxygen levels and production. The headspace analysis technology operates by passing a near-infrared diode laser light through the gas headspace region of the sealed container. 2.1.3. Figure 1 Linearity of the Lighthouse Instruments FMS-Oxygen headspace analyzer PDA Journal of GMP and Validation in Japan multiplying a by the maximum oxygen accumulation. The FMS-Oxygen is a non-destructive headspace oxygen analyzer from LIGHTHOUSE, the industry leader in laser-based headspace analysis. Directions. Scope of the Report Headspace Gas Analyzers by Category Product: Oxygen Headspace Analyzers Carbon Dioxide (CO2) Headspace Analyzers Combination Headspace Analyzers A new biological product, in pre-filled glass syringes, had demonstrated oxygen sensitivity in stability studies. Laser-based headspace analysis (HSA) measures light absorption by oxygen and/or water vapor molecules and rejects containers with elevated oxygen, pressure or moisture levels. Deterministic methods, like headspace analysis, predictably and quantitatively measure a physical or chemical endpoint to determine the closure integrity of a container. The FORENSICS oxygen headspace analyzer is an excellent option for those that would like to confirm O2 content within their packaging. on-site trouble shooting and support. Headspace moisture analysis is a rapid nondestructive analytical method that addresses the limitations of traditional methods used for residual moisture determination. Benchtop headspace analyzer Figure 2b: Headspace analysis system being used to monitor CCI of a lyophilized product. With the help of funding from the FDA, the method was first introduced by LIGHTHOUSE to the pharmaceutical industry in the late 1990's and has been adopted and WITH 7CASES OF ACCESSORIES WILL ADD PICS OF CONTENTS IN BAGS SERIAL # 651 MANUFACTURED 12/2017 PRETTY RECENT! In headspace analysis, the selection of sample vial is also critical. Lighthouse Instruments delivers laser-based headspace analyzer platforms and measurement services addressing a wide range of applications for monitoring sterile pharmaceutical processes and inspecting the quality of finished product. Featured topics this month are: Lighthouse and Bosch Announce Strategic Partnership The benchtop headspace oxygen analyzer can be used throughout the entire product lifecycle, from development to QC laboratory applications to at-line, in-process control of headspace oxygen levels and production. The FMS-Moisture/Pressure Headspace Analyzer is a non-destructive gas analyzer for simultaneously monitoring moisture partial pressure and total headspace pressure. Oxygen Headspace Instrumentation: FMS-760 Oxygen Headspace Analyzer Description: Uses Frequency Modulation Spectroscopy (FMS) to detect oxygen in the headspace of transparent rigid containers and measures rise or fall in the oxygen levels in the container's headspace to identify a potential leak. This rapid and versatile technology addresses a wide range of . The FMS-Moisture/Pressure is a non-destructive headspace moisture and pressure analyzer from LIGHTHOUSE, the industry leader in laser-based headspace analysis. Laser-Headspace Class 1-6 Gas Composition or Gas Pressure HVLD Class 3-6 Electrical Current Pressure Decay Class 3-6 Pressure Drop Vacuum Decay Class 3-6 Pressure Rise Mass Extraction Class 3-6 Mass Flow While no single method is appropriate for all types of containers, Laser Headspace analysis is the only method for all sizes of defects Claim this business. the system includes a light source housed in a light source housing and configured to emit a light beam for absorption in a substance to be measured, a detector housed in a detector housing and configured to detect the emitted light beam, a zone that accepts one or more of the sealed containers, each container being substantially optically Download this Product Note to find out more about the patented laser absorption technique, system specifications, performance data and industry applications. LIGHTHOUSE's FMS-Carbon Dioxide (CO2) Headspace Analyzer measures CO2 concentration in sealed parenteral containers for a variety of applications. In 2000 it created laser-based headspace analysis methods and equipment that have revolutionised how the pharmaceutical industry analyses products and packages, and it continues to develop new methods to generate . FMS-Oxygen headspace analyzer on 1 cc syringes. This rapid and versatile technology addresses a wide range of . One touch automated calibration and product analysis make these analyzers easy to use. When combined with a LIGHTHOUSE FMS Headspace Gas Analyzer, the CCI Test Vessel offers a robust solution for container integrity tests on a wide range of container types and packaging conditions. Sterilizers - Autoclaves. This rapid and versatile technology addresses a wide . Solutions for Container Closure Integrity testing, Oxygen monitoring, Moisture determination and Media fill inspection. Simply insert the needle tip of the probe into the food pack through a septa seal pad. Download this Case Study to learn how laser-based headspace analysis can be used as a tool to check package integrity and for the presence of reactive headspace gases that can degrade the formulation. LIGHTHOUSE continues to innovate the use of rapid, non-destructive headspace gas analysis. Download High Res Photos. Make an Inquiry Add To Watch List. Applications Include Depending on the inertness of sample . LIGHTHOUSE's FMS-Carbon Dioxide (CO2) Headspace Analyzer measures CO2 concentration in sealed parenteral containers for a variety of applications. (434) 293-3081. Solutions for Optimal Lyophilization. . Click here to download. Order Online. Dispersing & Homogenizing Solutions. LIGHTHOUSE's FMS-Water Activity Analyzer measures the water activity (% RH) of drug product samples. www.lighthouseinstruments.com parenteral container. This measurement method allows for the rapid analysis of 100% of product while reducing testing costs. Instrument: Us Lighthouse -- FMS-760. A recent market study by this publisher on the headspace gas analyzers market offers a global industry analysis for 2016-2020 and an opportunity assessment for 2021-2031. The FMS-1400 Headspace Moisture/Pressure Analyzer is a non-destructive gas analyzer for simultaneously monitoring moisture partial pressure and total headspace pressure. Light absorption, measured using frequency-modulated spectroscopy, is indicative of gas concentration. Analyzers; Lighthouse; Listing# 891501 Lighthouse FMS-760 Headspace Oxygen Analyzer; Listing# 891501 Lighthouse FMS-760 Headspace Oxygen Analyzer. TECHNOLOGY/APPLICATION The Application of Noninvasive Headspace Analysis to Media Fill Inspection DEREK DUNCAN1,*, TONY CUNDELL3, LAUREN LEVAC2, JAMES VEALE2, SUZANNE KUIPER1, and RAVI RAO1 1Lighthouse Instruments BV, Amsterdam, The Netherlands; 2Lighthouse Instruments LLC, Charlottesville, VA, USA; and 3Microbiological Consulting, LLC, Scarsdale, NY, USA PDA, Inc. 2016 Lighthouse Instruments, LLC Corporate Headquarters 2020 Avon Court, Suite #2 Charlottesville, VA 22902 Telephone: +1 (434) 293-3081 E-mail: info@lighthouseinstruments.com Response is typically less than five seconds for oxygen and ten seconds for carbon dioxide. . Laser headspace method. LIGHTHOUSE introduced the laser-based headspace method into the pharmaceutical industry in the late 1990s and offers a range of benchtop and in-line platforms with patented laser sensor technology. Why Lighthouse is a leader in its field. A system and method for nondestructive automated headspace analysis. Aug 25, 2022 (The Expresswire) -- [91 Pages] "Headspace Gas Analyzer Market" Insights 2022 By Types (types . Glass vial sample preparation LIGHTHOUSE FMS-760 OXYGEN HEADSPACE ANALYZER PN: 10E-880-120. The analyzer is a robust solid state device and is straightforward to use. The voltage changes based on the gas concentration and sensor output. The Lighthouse FMS-760 Headspace Oxygen Analyzer and FMS- 1400 Headspace Pressure Analyzer can be utilized for container closure studies of sterile product packaged under a nitrogen overlay or under full/partial vacuum. It is a useful analytical tool to generate statistical process and product data in all stages of the product life cycle, from Development to Manufacturing and Quality Control. "At Gilead we use Lighthouse's FMS benchtop headspace moisture/pressure analyzer to nondestructively confirm the integrity of developmental . The FMS-Oxygen is a non-destructive headspace oxygen analyzer from LIGHTHOUSE, the industry leader in laser-based headspace analysis. This compact benchtop instrument utilizes a patented laser absorption technique developed with funding from the Food and Drug Administration. The vessel creates an environment that accelerates this gas ingress through an open defect. In-situ Particle Characterization Solutions. Oxygen leak rate (sccs)0.209 atm a Application of laser headspace analysis to detecting leaks and permeation in syringes LIGHTHOUSE's FMS-Oxygen Headspace Analyzer measures oxygen concentration in sealed parenteral containers. The system includes a container conveyor that conveys a plurality of generally optically transparent sealed test containers through a pre-inspection region, an inspection region and a post-inspection region of the container conveyor, and that conveys at least one sealed reference container, through the inspection region. The LIGHTHOUSE laser-based headspace method shines light through the headspace to measure headspace oxygen concentrations in finished product containers (Figure 1). The compact benchtop instrument utilizes a patented laser absorption technique developed with funding from the Food and Drug Administration. Lighthouse Instruments. The FMS-Oxygen is a non-destructive headspace oxygen analyzer from LIGHTHOUSE, the industry leader in laser-based headspace analysis. LIGHTHOUSE's FMS-Pressure/Moisture Headspace Analyzer simultaneously monitors both moisture partial pressure and total headspace pressure. More. Having introduced laser-based headspace analysis into the pharmaceutical industry, LIGHTHOUSE offers both equipment and measurement services for container closure integrity . LIGHTHOUSE headspace oxygen analyzer platforms for rapid non-destructive headspace analysis can help streamline the monitoring of purge performance on the filling line. Vials were sealed with FluroTec -laminated elastomeric closures under ambient conditions and tested for seal integrity to ensure the crimping process was successful prior to placement in a cryogenic storage chamber for 8 . In 2018, LIGHTHOUSE Instruments LLC introduced FMS headspace gas analyzer with measurement time of 0.5-5.0 seconds and 21 CFR Part 11 compliant software for rapid detection of gas. LIGHTHOUSE's FMS-Pressure/Moisture Headspace Analyzer simultaneously monitors both moisture partial pressure and total headspace pressure. LIGHTHOUSE pioneered the creation of rapid, non-destructive headspace analysis. Here, we investigate possible primary packaging solutions for therapies requiring even colder storage temperatures down to cryogenic levels (-150C to -180C). Lab Reactors - REACTRON Systems. LIGHTHOUSE draws on its years of innovation and expertise to bring you top-of-the-line, personalized equipment to keep your products, and by extension patients, healthy and safe. The primary goals of the work presented herein were to demonstrate the viability of the nondestructive, deterministic method known as laser-based gas headspace analysis for evaluating container closure integrity and to provide a physical model for predicting leak rates for a variety of container volumes, headspace conditions, and defect sizes. LIGHTHOUSE Instruments introduced the laser headspace technology into the pharmaceutical industry more than 15 years ago and has the largest installed base of laser-based headspace systems worldwide. Lighthouse Instruments FMS. LIGHTHOUSE's FMS-Oxygen Headspace Analyzer measures oxygen concentration in sealed parenteral containers. The new more compact corrosion resistant enclosure minimizes the required foot print space on carts and table tops. We introduced laser-based headspace analysis platforms into the pharmaceutical industry in 2000 with the help of funding from the Food and Drug Administration. (434) 293-3081. Based on spectroscopic methods, the measurement is analytical, rapid and non-destructive. The PULSAR Headspace CCI Inspection Lease System is an automated 100% CCI inspection machine designed to inspect the CCI of sealed parenteral containers through the measurement of headspace oxygen and/or pressure.
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